SRGN Human, Serglycin Human Recombinant Protein, HEK | Boster PROTP10124-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

SRGN Human, Serglycin Human Recombinant Protein, HEK

catalog :

PROTP10124-1

quantity :

2 ug, 10 ug, 1 mg

product information

sku :

PROTP10124-1

status :

Enabled

name :

SRGN Human, Serglycin Human Recombinant Protein, HEK

gene name :

SRGN

price various sizes :

Sample: 2ug / $153 Regular: 10ug / $230 Bulk: 1mg / $4663

conjugate :

description :

Serglycin Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain (Tyr28-Leu158) containing a total of 137 amino acids, having a calculated molecular mass of 15.5kDa and fused to a 6 aa His tag at C-Terminus.

short description :

description1 :

Introduction . SRGN is identified as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells also hold a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is related to the macromolecular complex of granzymes and perforin that acts as a intermediary of granule-mediated apoptosis.

description2 :

Amino Acid Sequence YPTRRARYQW VRCNPDSNSA NCLEEKGPMF ELLPGESNKI PRLRTDLFPK TRIQDLNRIF PLSEDYSGSG FGSGSGSGSG SGSGFLTEME QDYQLVDESD AFHDNLRSLD RNLPSDSQDL GQHGLEEDFM L HHHHHH.

size :

2 ug, 10 ug, 1 mg

uniprot id :

P10124

host :

form :

Filtered colorless solution.

purification :

Greater than 95.0% as determined by SDS-PAGE.

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

synonyms :

Serglycin;Hematopoietic proteoglycan core protein;Platelet proteoglycan core protein;P.PG;Secretory granule proteoglycan core protein;SRGN;PRG, PRG1;

gene full name :

Serglycin

protein function :

Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF- alpha and may also regulate protease secretion. Inhibits bone mineralization.

subcellular localization :

Cytoplasmic granule

source :

HEK 293.

last modified :

4/18/19 6:56