Activin-A Activin A Human Recombinant Protein, Plant | Boster PROTP08476 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

Activin-A Activin A Human Recombinant Protein, Plant

catalog :

PROTP08476

quantity :

2 ug, 10 ug, 1 mg

product information

SKU :

PROTP08476

Product Name :

Activin-A Activin A Human Recombinant Protein, Plant

Product Page URL :

https://www.bosterbio.comactivin-a-activin-a-human-recombinant-protein-plant-protp08476-boster.html

Gene Name :

INHBA

Size :

2 ug, 10 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: Activins are homodimers or heterodimers of the different ? subunit isoforms, part of the TGF? family. Mature Activin A has two 116 amino acids residues betaA subunits (bA-bA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.

Description :

Activin A human Recombinant produced in Nicotiana benthamiana plant is a disulfide-linked homodimers of two betaA chains, each containing 116 amino residues (molecular formula C600H911N173O174S13) and 6-His-tag at the N-terminal having the total molecular mass of 27.4kDa.

Source :

Nicotiana benthamiana plant

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

Contents :

Lyophilized from 1mg/ml solution in Tris HCl 0.05M buffer at pH 7.4.

AA Sequence and/or Biological Activity :

Amino Acid Sequence:HHHHHHGLEC DGKVNICCKK QFFVSFKDIG WNDWIIAPSG YHANYCEGEC PSHIAGTSGS SLSFHSTVIN HYRMRGHSPF ANLKSCCVPT KLRPMSMLYY DDGQNIIKKD IQNMIVEECG CS

Purification :

Greater than 97.0% as determined by Analysis by SDS-PAGE.

Storage :

Lyophilized Activin A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Activin A should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Uniprot ID :

P08476

Gene Full Name :

Inhibin beta A chain

Synonyms :

Inhibin beta A chain;Activin beta-A chain;Erythroid differentiation protein;EDF;INHBA;

Protein Function :

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Subcellular Localization :

Secreted.