Activin-A Human Recombinant Protein, Active | Boster PROTP08476-2 product information

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product summary

company name :

Boster

product type :

protein

product name :

Activin-A Human Recombinant Protein, Active

catalog :

PROTP08476-2

quantity :

2 ug, 10 ug, 1 mg

product information

sku :

PROTP08476-2

status :

Enabled

name :

Activin-A Human Recombinant Protein, Active

gene name :

INHBA

price various sizes :

Sample: 2ug / $153 Regular: 10ug / $230 Bulk: 1mg / $3863

conjugate :

contents :

Human Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 0.02% TFA.

description :

Active form Activin-A Human Recombinant produced in e.coli is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 117 amino acids and having a molecular weight of 26.2kDa. The Active form Activin-A is purified by standard chromatographic techniques.

short description :

description1 :

Introduction . Activins are homodimers or heterodimers of the different ? subunit isoforms, part of the TGF? family. Mature Activin A has two 116 amino acids residues ?A subunits (?A-?A). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.

description2 :

Amino Acid Sequence . MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS. Biological Activity . Biological activity is assessed by the ability to induce cytoxicity of MPC-11 cells and was found to be 1-1.5 ng/ml corresponding to a specific activity of 666,667-1,000,000 Units/mg.

size :

2 ug, 10 ug, 1 mg

uniprot id :

P08476

host :

form :

Lyophilized freeze dried powder.

purification :

Greater than 95% as obsereved by SDS-PAGE.

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

synonyms :

Inhibin beta A chain;Activin beta-A chain;Erythroid differentiation protein;EDF;INHBA;

gene full name :

Inhibin beta A chain

protein function :

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

subcellular localization :

Secreted.

source :

E.Coli

last modified :

2/18/19 20:29