EGF Epidermal Growth Factor Rat protein | Boster PROTP07522 product information

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product summary

company name :

Boster

product type :

protein

product name :

EGF Epidermal Growth Factor Rat protein

catalog :

PROTP07522

quantity :

2 ug, 5 ug, 10 ug

product information

SKU :

PROTP07522

Product Name :

EGF Epidermal Growth Factor Rat protein

Product Page URL :

https://www.bosterbio.comegf-epidermal-growth-factor-rat-protein-protp07522-boster.html

Gene Name :

Egf

Size :

2 ug, 5 ug, 10 ug

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide. EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.

Description :

Epidermal Growth Factor Rat purified from submandibular gland is a single, glycosylated, polypeptide chain having a molecular mass of 6.15 kDa. The EGF is purified by proprietary chromatographic techniques.

Source :

Adult Male Rat Submandibular Glands.

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

Contents :

The protein was lyophilized from a concentrated (1mg/ml) solution containing 0.01M sodium acetate buffer.

Purification :

Greater than 99.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Storage :

Lyophilized Epidermal Growth Factor Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EGF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Uniprot ID :

P07522

Gene Full Name :

Pro-epidermal growth factor

Synonyms :

Pro-epidermal growth factor;EGF;Epidermal growth factor;Egf;

Protein Function :

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).

Subcellular Localization :

Membrane; Single-pass type I membrane protein.