KLK1 Kallikrein-1 Human Recombinant Protein | Boster PROTP06870 product information

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product summary

company name :

Boster

product type :

protein

product name :

KLK1 Kallikrein-1 Human Recombinant Protein

catalog :

PROTP06870

quantity :

20 ug, 100 ug, 1 mg

product information

SKU :

PROTP06870

Product Name :

KLK1 Kallikrein-1 Human Recombinant Protein

Product Page URL :

https://www.bosterbio.comklk1-kallikrein-1-human-recombinant-protein-protp06870-boster.html

Gene Name :

KLK1

Size :

20 ug, 100 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: Kallikreins are serine protease enzymes having various physiological functions. Kallikreins are implicated in carcinogenesis and have potenital as novel cancer disease biomarkers. KLKthe fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLKbradykininogen to bradykinin. Kallikrein-1, which derived from human or porcine, have been used as drugs for a long time, they are mainly used in the treatment f light to medium hypertension and occlusion of cerebral and surrounding blood vessels. KLKhuman umbilical veins. The K allele of KLKTGF-betaKLKKLK1on the surface which is important function in maintenance of circulation homeostasis. KLKdesmoglein 1 and regulation by lympho-epithelial Kazal-type-related inhibitor (LEKTI).

Description :

KLK1 Human Recombinant produced in Yeast is a single, glycosylated, polypeptide chain containing 238 amino acids and having a molecular mass of 28-32 kDa. KLK1 Human Recombinant is purified by proprietary chromatographic techniques.

Source :

Pichia Pastoris.

Form :

Sterile Filtered white lyophilized powder.

Contents :

Lyophilized from a solution containing 1xPBS.

AA Sequence and/or Biological Activity :

Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Ile-Val-Gly-Gly-Trp-Glu.

Purification :

Greater than 98.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Storage :

Store KLK1 at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

Uniprot ID :

P06870

Gene Full Name :

Kallikrein-1

Synonyms :

Kallikrein-1;3.4.21.35;Kidney/pancreas/salivary gland kallikrein;Tissue kallikrein;KLK1;

Protein Function :

Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Tissue Specificity :

Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.