Recombinant Human IL-6 Protein | Boster PROTP05231-4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

Recombinant Human IL-6 Protein

catalog :

PROTP05231-4

quantity :

Various Sizes

product information

sku :

PROTP05231-4

status :

Enabled

name :

Recombinant Human IL-6 Protein

category name :

Proteins, Recombinant Proteins

gene name :

IL6

price various sizes :

5ug / $125 20ug / $230 50ug / $438 100ug / $698 250ug / $1184 500ug / $1994 1mg / $3290

conjugate :

contents :

Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.

description :

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.

short description :

description2 :

Biological Activity And Protein Authenticity . The ED 50 as determined by the dose-dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells is 0.1 ng/ml, corresponding to a specific activity of 1 x 10 7 units/mg.

size :

Various Sizes

uniprot id :

P05231

host :

form :

Solid; white powder or thin/invisible film

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

research category :

Angiogenesis, Cancer, Cytokines, Immunology, Innate Immunity, Interleukins, Invasion/Microenvironment, Metabolism, Neurology Process, Neuroscience, Obesity, Tumor Immunology

synonyms :

Interleukin-6;IL-6;B-cell stimulatory factor 2;BSF-2;CTL differentiation factor;CDF;Hybridoma growth factor;Interferon beta-2;IFN-beta-2;IL6;IFNB2; 26 kDa protein, IFN- 2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2

gene full name :

Interleukin-6

protein function :

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

subcellular localization :

Secreted.

source :

E. Coli

last modified :

2/15/19 23:59