This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
protein
product name :
Recombinant Human IL-1 Alpha Protein
catalog :
PROTP01583-3
quantity :
Various Sizes
product information
sku :
PROTP01583-3
status :
Enabled
name :
Recombinant Human IL-1 Alpha Protein
category name :
Proteins, Recombinant Proteins
gene name :
IL1A
price various sizes :
2ug / $125 10ug / $230 50ug / $471 100ug / $752 250ug / $1278 500ug / $2156 1mg / $3560
conjugate :
No
contents :
Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
description :
IL-1 is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 and IL-1 binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 is a secreted cytokine, IL-1 is predominantly a cell-associated cytokine. Recombinant human IL-1 is an 18.0 kDa protein containing 159 amino acid residues.
short description :
IL-1 is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 and IL-1 binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 is a secreted cytokine, IL-1 is predominantly a cell-associated cytokine. Recombinant human IL-1 is an 18.0 kDa protein containing 159 amino acid residues.
description2 :
Biological Activity And Protein Authenticity . The ED 50 as determined by the dose-dependent stimulation of murine D10S cells is 0.001 ng/ml, corresponding to a specific activity of 1 x 10 9 units/mg.
size :
Various Sizes
uniprot id :
P01583
host :
No
form :
Solid; white powder or thin/invisible film
storage :
Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.
applications :
Cell Culture
image labels :
Recombinant protein fun image
research category :
Cancer, Cytokines, Immunology, Innate Immunity, Interleukins, Tumor Immunology
synonyms :
Interleukin-1 alpha;IL-1 alpha;Hematopoietin-1;IL1A;IL1F1; Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
gene full name :
Interleukin-1 alpha
protein function :
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
subcellular localization :
Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
source :
E. Coli
last modified :
2/15/19 23:59
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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