Recombinant Human IL-33 Protein | Boster PROTO95760-2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

Recombinant Human IL-33 Protein

catalog :

PROTO95760-2

quantity :

Various Sizes

product information

sku :

PROTO95760-2

status :

Enabled

name :

Recombinant Human IL-33 Protein

category name :

Proteins, Recombinant Proteins

gene name :

IL33

price various sizes :

2ug / $125 10ug / $230 50ug / $611 100ug / $986 250ug / $1688 500ug / $2858 1mg / $4730

conjugate :

contents :

Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.

description :

Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.

short description :

description2 :

Biological Activity And Protein Authenticity . The ED 50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is 0.05 ng/ml, corresponding to a specific activity of 2 x 10 7 units/mg.

size :

Various Sizes

uniprot id :

O95760

host :

form :

Solid; white powder or thin/invisible film

storage :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

applications :

Cell Culture

image labels :

Recombinant protein fun image

research category :

Angiogenesis, Cardiovascular, Cytokines, Hypertrophy, Immunology, Innate Immunity, Interleukins

synonyms :

Interleukin-33;IL-33;Interleukin-1 family member 11;IL-1F11;Nuclear factor from high endothelial venules;NF-HEV;Interleukin-33 (95-270);Interleukin-33 (99-270);Interleukin-33 (109-270);IL33;C9orf26, IL1F11, NFHEV; NF-HEV

gene full name :

Interleukin-33

protein function :

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528).

subcellular localization :

Nucleus . Chromosome . Cytoplasmic vesicle, secretory vesicle . Secreted . Associates with heterochromatin and mitotic chromosomes (PubMed:17185418).

tissue specificity :

Expressed at high level in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes. Almost undetectable in placenta.

source :

E. Coli

last modified :

2/15/19 23:59