Fractalkine Rat Recombinant Protein (CX3CL1) | Boster PROTO55145 product information

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product summary

company name :

Boster

product type :

protein

product name :

Fractalkine Rat Recombinant Protein (CX3CL1)

catalog :

PROTO55145

quantity :

5 ug, 20 ug, 1 mg

product information

SKU :

PROTO55145

Product Name :

Fractalkine Rat Recombinant Protein (CX3CL1)

Product Page URL :

https://www.bosterbio.comfractalkine-rat-recombinant-protein-cx3cl1-proto55145-boster.html

Gene Name :

Cx3cl1

Size :

5 ug, 20 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: Fractalkine soluble form is chemotactic for t-cells and monocytes, but not for neutrophils. Fractalkine membrane-bound form promotes adhesion of those leukocytes to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the cell surface. Fractalkine gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22.

Description :

Fractalkine Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8.7kDa. The Fractalkine is purified by proprietary chromatographic techniques.

Source :

E. Coli

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

AA Sequence and/or Biological Activity :

Amino Acid Sequence:QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG Biological Activity:Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml, corresponding to a specific activity of 100,000-200,000units/mg.

Purification :

Greater than 97.0% as determined by SDS-PAGE.

Storage :

Lyophilized FractalkineRat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Fractalkine should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

Uniprot ID :

O55145

Gene Full Name :

Fractalkine

Synonyms :

Fractalkine;C-X3-C motif chemokine 1;CX3C membrane-anchored chemokine;Neurotactin;Small-inducible cytokine D1;Processed fractalkine;Cx3cl1;Acc1, Fkn, Scyd1;

Protein Function :

The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.

Subcellular Localization :

Cell membrane

Tissue Specificity :

Highest levels in brain (neurons). Significant levels in kidney, heart, lung and adrenal gland.