BCA-1/BLC Mouse Recombinant Protein (CXCL13) | Boster PROTO55038 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

protein

product name :

BCA-1/BLC Mouse Recombinant Protein (CXCL13)

catalog :

PROTO55038

quantity :

5 ug, 20 ug, 1 mg

product information

SKU :

PROTO55038

Product Name :

BCA-1/BLC Mouse Recombinant Protein (CXCL13)

Product Page URL :

https://www.bosterbio.combca-1-blc-mouse-recombinant-protein-cxcl13-proto55038-boster.html

Gene Name :

Cxcl13

Size :

5 ug, 20 ug, 1 mg

Reactivity :

Mouse

Applications :

Cell Culture

Introduction :

Introduction: BCA-the spleen, lymph nodes, and Peyer's patches. CXCL13 promotes the migration of B lymphocytes (compared to T cells and macrophages), by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor B lymphocytes to follicles. Human BCA-the hematopoietic lineages, the expression of BLR-1, now designated CXCR-5, is restricted to B lymphocytes and a subpopulation of T helper memory cells.

Description :

CXCL13 Mouse Recombinant (22-109) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 10kDa. The BCA-1 is purified by proprietary chromatographic techniques.

Source :

E. Coli

Form :

Sterile Filtered White lyophilized (freeze-dried) powder.

AA Sequence and/or Biological Activity :

Amino Acid Sequence: ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA.

Purification :

Greater than 97.0% as determined by SDS-PAGE.

Storage :

Lyophilized BCA1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BCA1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Uniprot ID :

O55038

Gene Full Name :

C-X-C motif chemokine 13

Synonyms :

C-X-C motif chemokine 13;B lymphocyte chemoattractant;CXC chemokine BLC;Small-inducible cytokine B13;Cxcl13;Blc, Scyb13;

Protein Function :

Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.

Subcellular Localization :

Secreted.

Tissue Specificity :

Found in spleen (B-cell-rich zone or follicles), Peyer patches (strongest within germinal centers and extending to the mantle zone) and lymph nodes (in reticular pattern in follicles).