Anti-CYP11A1 Picoband Antibody | Boster PB9942 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CYP11A1 Picoband Antibody

catalog :

PB9942

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot

product information

sku :

PB9942

status :

Enabled

name :

Anti-CYP11A1 Picoband Antibody

category name :

Primary Antibodies, Polyclonal Antibodies

gene name :

CYP11A1

price various sizes :

30ug sample size / $99 100ug / $240 100ug+Free HRP Secondary BA1054 / $240 100ug+Free Biotin Secondary BA1003 / $240

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

description :

Polyclonal antibody for CYP11A1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. CYP11A1 information: Molecular Weight: 60102 MW; Subcellular Localization: Mitochondrion membrane.

short description :

Rabbit IgG polyclonal antibody for Cholesterol side-chain cleavage enzyme, mitochondrial(CYP11A1) detection. Tested with WB in Human;Rat.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

P05108

host :

Rabbit

immunogen :

E. coli-derived human CYP11A1 recombinant protein (Position: M333-A418). Human CYP11A1 shares 89.5% amino acid (aa) sequence identity with both mouse and rat CYP11A1.

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Western blot, 0.1-0.5ug/ml, Human, Rat.

applications :

reactivity :

Human, Rat

image labels :

Western blot analysis of CYP11A1 expression in rat brain extract (lane 1), rat kidney extract (lane 2) and 293T whole cell lysates (lane 3). CYP11A1 at 75KD was detected using rabbit anti-CYP11A1 Antigen Affinity purified polyclonal antibody (Catalog # PB9942) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002).

background :

CYP11A1 (Cytochrome p450, family 11, subfamily A, polypeptide 1), commonly referred to as P450scc, is a mitochondrial enzyme associated with the conversion of cholesterol to pregnenolone. CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The CYP11A1 gene is mapped on 15q24.1. Expression of the CYP11A1 gene may play a role in skin physiology and pathology and that cutaneous proopiomelanocortin activity may be autoregulated by a feedback mechanism involving glucocorticoids synthesized locally. Using in vitro studies, CYP11A1 catalyzed the side-chain cleavage of 7-dehydrocholesterol to form 7-dehydropregnenolone. In addition, CYP11A1 catalyzed the metabolism of biologically inert vitamin D3, which is formed from 7-dehydrocholesterol, to form 2 hydroxylated products, 20-hydroxyvitamin D3 and 20, 22-dihydroxyvitamin D3. Mutations in the CYP11A1 gene cause congenital adrenal insufficiency with partial or complete 46, XY sex reversal.

competitor equivalent skus :

sc 292456 sc 18040 sc 18043

research category :

Cancer, Cancer Metabolism, Cardiovascular, Cholesterol Metabolism, Cytochromes, Endocrine Metabolism, Growth Factors/Hormones, Hormone Biosynthesis, Lipases, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Lipids / Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Lipids And Lipoproteins, Mitochondrial Metabolism, Pathways And Processes, Signal Transduction

synonyms :

Cholesterol side-chain cleavage enzyme, mitochondrial;1.14.15.6;CYPXIA1;Cholesterol desmolase;Cytochrome P450 11A1;Cytochrome P450(scc);CYP11A1;CYP11A;

gene full name :

Cholesterol side-chain cleavage enzyme, mitochondrial

molecular weight :

60102 MW

protein function :

Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.

subcellular localization :

Mitochondrion membrane.

protein name :

Cholesterol side-chain cleavage enzyme, mitochondrial

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

last modified :

1/28/19 19:39