Anti-Surfactant protein D/SFTPD Antibody Picoband™ | Boster PB9617 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Surfactant protein D/SFTPD Antibody Picoband™

catalog :

PB9617

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

PB9617

Product Name :

Anti-Surfactant protein D/SFTPD Antibody Picoband™

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Rat

Application(s) :

ELISA, IHC, ICC, WB

Application Details :

ELISA, 0.1-0.5µg/mlImmunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, By Heat.Immunohistochemistry (Frozen Section), 0.5-1µg/ml.Immunocytochemistry, 0.5-1µg/ml Western blot, 0.1-0.5µg/ml.

Application Notes :

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Surfactant protein D/SFTPD Antibody Picoband™ catalog # PB9617. Tested in ELISA, IHC, ICC, WB applications. This antibody reacts with Human, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

SFTPD

Uniprot ID :

P35247

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Surfactant protein D (292-321aa RSAAENAALQQLVVAKNEAAFLSMTD SKTE), different from the related mouse and rat sequences by eight amino acids.

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Pulmonary surfactant-associated protein D

Synonyms :

Pulmonary surfactant-associated protein D; PSP-D; SP-D; Collectin-7; Lung surfactant protein D; SFTPD; COLEC7, PSPD, SFTP4;

Protein Name :

Pulmonary surfactant-associated protein D

Molecular Weight :

37728 MW

Protein Function :

Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Tissue Specificity :

Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.

Sequence Similarities :

Belongs to the SFTPD family.

Background :

Surfactant, pulmonary-associated protein D, also known as SFTPD or SP-D, is a protein which in humans is encoded by the SFTPD gene. It is mapped to 10q22.2-q23.1. The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism.

Research Category :

Calcium Binding Proteins, Calcium Signaling, Cancer, Cancer Metabolism, Cell Biology, Defensin, Human Protein, Immunology, Innate Immunity, Macrophage / Inflamm., Metabolism, Microbiology, Oxidative Stress, Pathways And Processes, Protein, Redox Metabolism, Signal Transduction, Signaling Pathway