Anti-alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody Picoband™

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody Picoband™

catalog :

PB9482

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot

product information

SKU :

PB9482

Product Name :

Anti-alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody Picoband™

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Monkey

Application(s) :

Application Details :

Western blot, 0.1-0.5µg/ml, Human, Monkey.

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody Picoband™ catalog # PB9482. Tested in WB applications. This antibody reacts with Human, Monkey.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

ATP1A1

Uniprot ID :

P05023

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human ATP1A1 (7-34aa RDKYEPAAVSEQGDKKGKKGKKDRDMDE), different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Sodium/potassium-transporting ATPase subunit alpha-1

Synonyms :

Sodium/potassium-transporting ATPase subunit alpha-1; Na (+)/K (+) ATPase alpha-1 subunit; 3.6.3.9; Sodium pump subunit alpha-1; ATP1A1;

Protein Name :

Sodium/potassium-transporting ATPase subunit alpha-1

Molecular Weight :

112896 MW

Protein Function :

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Subcellular Localization :

Cell membrane; Multi-pass membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Category :

Atpases, Cancer, Cancer Metabolism, Cell Type Marker, Metabolism, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Plasma Membrane, Response To Hypoxia, Signal Transduction, Subcellular Markers, Synapse Marker, Tags & Cell Markers