Anti-TAB1 Picoband Antibody | Boster PB9445 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-TAB1 Picoband Antibody

catalog :

PB9445

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot

product information

sku :

PB9445

status :

Enabled

name :

Anti-TAB1 Picoband Antibody

category name :

Primary Antibodies, Polyclonal Antibodies

gene name :

TAB1

price various sizes :

30ug sample size / $99 100ug / $240 100ug+Free HRP Secondary BA1054 / $240 100ug+Free Biotin Secondary BA1003 / $240

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

description :

Polyclonal antibody for TAB1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. TAB1 information: Molecular Weight: 54644 MW; Tissue Specificity: Ubiquitous.

short description :

Rabbit IgG polyclonal antibody for TGF-beta-activated kinase 1/MAP3K7-binding protein 1(TAB1) detection. Tested with WB in Human;Rat.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

Q15750

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human TAB1 (78-108aa NFVAQRLSAELLLGQLNAEHAEADVRRVLLQ), different from the related mouse sequence by two amino acids.

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Western blot, 0.1-0.5ug/ml, Human, Rat.

applications :

reactivity :

Human, Rat

image labels :

Anti- TAB1 Picoband antibody, PB9445, Western blotting. All lanes: Anti TAB1 (PB9445) at 0.5ug/ml. Lane 1: Rat Liver Tissue Lysate at 50ug. Lane 2: Rat Lung Tissue Lysate at 50ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A549 Whole Cell Lysate at 40ug. Lane 5: JURKAT Whole Cell Lysate at 40ug. Predicted bind size: 55KD. Observed bind size: 72KD

background :

Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, also called TAB1, is an enzyme that in humans is encoded by the MAP3K7IP1 gene. It is mapped to 22q13.1. The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways. This protein can interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. TAB1 also can activate the kinase activity of TAK1 by direct interaction, and it may be an important signaling intermediate between TGFB receptors and TAK1. What's more, TAB1 plays an important role in skin homeostasis, wound repair, and oncogenesis.

competitor equivalent skus :

sc 6052 sc 13956 sc 6053 sc 100869 sc 166138

research category :

Atherosclerosis, Cardiovascular, Immunology, Innate Immunity, Mapk Pathway, Protein Phosphorylation, Ser / Thr Kinases, Signal Transduction, Tlr Signaling, Vascular Inflammation

synonyms :

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1;Mitogen-activated protein kinase kinase kinase 7-interacting protein 1;TGF-beta-activated kinase 1-binding protein 1;TAK1-binding protein 1;TAB1;MAP3K7IP1;

gene full name :

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

molecular weight :

54644 MW

protein function :

May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.

tissue specificity :

Ubiquitous.

protein name :

TGF-beta-activated kinase 1/MAP3K7-binding protein 1

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

sequence similarities :

Contains 1 PPM-type phosphatase domain.

last modified :

1/28/19 19:39