Anti-Kallikrein 4/KLK4 Antibody Picoband™ | Boster PB9260 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Kallikrein 4/KLK4 Antibody Picoband™

catalog :

PB9260

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

SKU :

PB9260

Product Name :

Anti-Kallikrein 4/KLK4 Antibody Picoband™

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Application(s) :

Application Details :

Western blot, 0.1-0.5µg/ml, Human.

Application Notes :

WB: The detection limit for Kallikrein 4 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Kallikrein 4/KLK4 Antibody Picoband™ catalog # PB9260. Tested in WB applications. This antibody reacts with Human.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

KLK4

Uniprot ID :

Q9Y5K2

Immunogen :

E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254).

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Kallikrein-4

Synonyms :

Kallikrein-4; 3.4.21.-; Enamel matrix serine proteinase 1; Kallikrein-like protein 1; KLK-L1; Prostase; Serine protease 17; KLK4; EMSP1, PRSS17, PSTS;

Protein Name :

Kallikrein-4

Molecular Weight :

27032 MW

Protein Function :

Involved in enamel formation.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in prostate.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Sequence Similarities :

Belongs to the peptidase S1 family. Kallikrein subfamily.

Background :

Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.

Research Category :

Cancer, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Proteolysis / Ubiquitin, Proteolytic Enzymes, Signal Transduction