Anti-Vasopressin V1a receptor AVPR1A Antibody | Boster PA2248 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Vasopressin V1a receptor AVPR1A Antibody

catalog :

PA2248

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

SKU :

PA2248

Product Name :

Anti-Vasopressin V1a receptor AVPR1A Antibody

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Predicted Reactivity :

Hamster

Application(s) :

Application Details :

Western blot, 0.1-0.5µg/ml, Human, Rat, Mouse.

Application Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Vasopressin V1a receptor AVPR1A Antibody catalog # PA2248. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

AVPR1A

Uniprot ID :

P30560

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of rat AVPR1A (155-173aa HPLKTLQQPARRSRLMIAT), different from the related human and mouse sequences by one amino acid.

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Vasopressin V1a receptor

Synonyms :

Vasopressin V1a receptor; V1aR; AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor; Avpr1a;

Protein Name :

Vasopressin V1a receptor

Molecular Weight :

47655 MW

Protein Function :

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Involved in social memory formation.

Subcellular Localization :

Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Located in cytoplasmic vesicles dispersed throughout the cell cytoplasm and to the plasma membrane.

Tissue Specificity :

Localized within gonadotropes of the anterior pituitary of the brain. Broadly distributed throughout the cerebral cortex.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Sequence Similarities :

Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Background :

Arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for arginine vasopressin (AVPR1B and AVPR2 being the others). It belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. This gene is mapped to 12q14.2. AVPR1A is present throughout the brain, as well as in the periphery, in the liver, kidney, and vasculature. The protein encoded by this gene acts as receptor for arginine vasopressin. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

Research Category :

G Protein Signaling, More Gpcr, Neurology Process, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway