Anti-TLR2 Antibody | Boster PA2247 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-TLR2 Antibody

catalog :

PA2247

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

sku :

PA2247

name :

Anti-TLR2 Antibody

price :

200 USD

immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human TLR2(364-379aa YLDLSENLMVEEYLKN), different from the related mouse and rat sequences by one amino acid.

form :

Lyophilized

host :

Rabbit

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

purification :

Immunogen affinity purified.

clonality :

Polyclonal

description :

Rabbit IgG polyclonal antibody for Toll-like receptor 2(TLR2) detection. Tested with WB in Human;Mouse;Rat.

size :

100 ug/vial

reactivity :

Human; Mouse; Rat

applications :

background :

Toll-like receptor 2 also known as TLR-2 is a protein that in humans is encoded by the TLR2 gene. TLR2 has also been designated as CD282(cluster of differentiation 282). TLR-2 plays a role in the immune system. TLR-2 is a membrane protein, a receptor, which is expressed on the surface of certain cells and recognizes foreign substances and passes on appropriate signals to the cells of the immune system. TLR2 expresses as 4- and 4.4-kb mRNAs in heart, brain, and muscle.

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

cross reactivity :

No cross reactivity with other proteins

gene full name :

Toll-like receptor 2

gene name :

TLR2

predicted reactivity :

Chicken

protein function :

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

protein name :

Toll-like receptor 2

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

research category :

immunology innate immunity macrophage / inflamm. immunology immunoglobulins receptors microbiology protein human protein defensin signal transduction adapters transmembrane cardiovascular atherosclerosis vascular inflammation inflammatory mediators tlr signaling

sequence similarities :

Belongs to the Toll-like receptor family.

storage :

At -20ËšC for one year. After reconstitution, at 4ËšC for one month. It can also be aliquotted and stored frozen at -20ËšC for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Membrane ; Single-pass type I membrane protein .

synonyms :

Toll-like receptor 2;Toll/interleukin-1 receptor-like protein 4;CD282;TLR2;TIL4;

tissue specificity :

Highly expressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, lymph node and in spleen. Also detected in lung and in fetal liver. Levels are low in other tissues.

uniprot id :

O60603