Anti-SGLT1/SLC5A1 Antibody | Boster PA2244 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-SGLT1/SLC5A1 Antibody

catalog :

PA2244

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

SKU :

PA2244

Product Name :

Anti-SGLT1/SLC5A1 Antibody

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Rat, Mouse, Human

Predicted Reactivity :

Hamster

Application(s) :

Application Details :

Western blot, 0.1-0.5µg/ml, Human, Rat, Mouse.

Application Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-SGLT1/SLC5A1 Antibody catalog # PA2244. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

SLC5A1

Uniprot ID :

P13866

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of mouse SGLT1 (620-635aa KMTKEEEEAMKMKMTD), different from the related rat sequence by one amino acid, and from the related human sequence by two amino acids.

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Sodium/glucose cotransporter 1

Synonyms :

Sodium/glucose cotransporter 1; Na (+)/glucose cotransporter 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1; SLC5A1; NAGT, SGLT1;

Protein Name :

Sodium/glucose cotransporter 1

Molecular Weight :

73498 MW

Protein Function :

Actively transports glucose into cells by Na (+) cotransport with a Na (+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na (+)/glucose cotransporter arranged in series along kidney proximal tubules.

Subcellular Localization :

Membrane; Multi-pass membrane protein.

Tissue Specificity :

Expressed mainly in intestine and kidney.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

Sodium/glucose cotransporter 1 (SLC5A1), also known as NAGT or SGLT1 is a protein that in humans is encoded by the SLC5A1 gene. This gene is mapped to 22q12.3. This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Category :

Channels, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Plasma Membrane, Signal Transduction