Anti-CD47 Antibody | Boster PA2223 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD47 Antibody

catalog :

PA2223

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

sku :

PA2223

status :

Enabled

name :

Anti-CD47 Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

CD47

price various sizes :

30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

description :

Polyclonal antibody for CD47 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. CD47 information: Molecular Weight: 35214 MW; Subcellular Localization: Cell membrane ; Multi-pass membrane protein ; Tissue Specificity: Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.

short description :

Rabbit IgG polyclonal antibody for Leukocyte surface antigen CD47(CD47) detection. Tested with WB, IHC-P in Human;Rat.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

Q08722

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human CD47(308-323aa EPLNAFKESKGMMNDE), identical to the related rat sequence.

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, By Heat. Western blot, 0.1-0.5ug/ml, Rat, Human.

applications :

IHC, WB

reactivity :

Human, Rat

predicted reactivity :

Hamster

image labels :

Anti-CD47 antibody, PA2223, IHC(P). IHC(P): Human Placenta Tissue Anti-CD47 antibody, PA2223, Western blotting. All lanes: Anti CD47 (PA2223) at 0.5ug/ml. WB: Rat Brain Tissue Lysate at 50ug. Predicted bind size: 35KD. Observed bind size: 35KD

background :

CD47, also known as IAP or MER6, is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 gene belongs to the immunoglobulin superfamily. This gene is mapped to 3q13.12. CD47 gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

competitor equivalent skus :

sc 12731 sc 7059 sc 25773 sc 21786 sc 7057 sc 59079 sc 12730 sc 53050 sc 70716

research category :

Cell Type Markers, Immunology, Tumor Immunology

synonyms :

Leukocyte surface antigen CD47;Antigenic surface determinant protein OA3;Integrin-associated protein;IAP;Protein MER6;CD47;CD47;MER6;

gene full name :

Leukocyte surface antigen CD47

molecular weight :

35214 MW

protein function :

Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

subcellular localization :

Cell membrane ; Multi-pass membrane protein .

tissue specificity :

Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.

protein name :

Leukocyte surface antigen CD47

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

last modified :

1/28/19 19:39