Anti-Monocarboxylic acid transporter 1/SLC16A1 Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Monocarboxylic acid transporter 1/SLC16A1 Antibody

catalog :

PA2188

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

PA2188

status :

Enabled

name :

Anti-Monocarboxylic acid transporter 1/SLC16A1 Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

SLC16A1

price various sizes :

30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

description :

Polyclonal antibody for MCT1/SLC16A1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. MCT1/SLC16A1 information: Molecular Weight: 53944 MW; Subcellular Localization: Cell membrane ; Multi- pass membrane protein ; Tissue Specificity: Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed.

short description :

Rabbit IgG polyclonal antibody for Monocarboxylate transporter 1(SLC16A1) detection. Tested with WB, IHC-P in Human.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

P53985

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human Monocarboxylic acid transporter 1(236-254aa RHPKQEKRSVFQTINQFLD).

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat. Western blot, 0.1-0.5ug/ml, Human.

applications :

IHC, WB

reactivity :

Human

image labels :

Anti-Monocarboxylic acid transporter 1 antibody, PA2188, Western blotting. Lane 1: COLO320 Cell Lysate. Lane 2: SKOV Cell Lysate. Lane 3: A549 Cell Lysate Anti-Monocarboxylic acid transporter 1 antibody, PA2188, IHC(P). IHC(P): Human Rectal Cancer Tissue

background :

Monocarboxylate transporter 1, also called SLC16A1 or MCT1 is a protein that in humans is encoded by the SLC16A1 gene. This gene is mapped to 1p13.2. This gene acts as Proton-linked monocarboxylate transporter. It catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.

competitor equivalent skus :

sc 100477 sc 14916 sc 14917 sc 365501 sc 366137 sc 390858 sc 50324 sc 86725 sc 86727

synonyms :

Monocarboxylate transporter 1;MCT 1;Solute carrier family 16 member 1;SLC16A1;MCT1;

gene full name :

Monocarboxylate transporter 1

molecular weight :

53944 MW

protein function :

Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

subcellular localization :

Cell membrane ; Multi- pass membrane protein .

tissue specificity :

Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed.

protein name :

Monocarboxylate transporter 1

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

sequence similarities :

Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

last modified :

1/28/19 19:39