Anti-Bonzo/CXCR6 Antibody | Boster PA2082-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Bonzo/CXCR6 Antibody

catalog :

PA2082-1

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

PA2082-1

Product Name :

Anti-Bonzo/CXCR6 Antibody

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Mouse, Rat

Predicted Reactivity :

Hamster

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Rat, Mouse, By Heat. Western blot, 0.1-0.5µg/ml, Mouse, Rat.

Application Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Bonzo/CXCR6 Antibody catalog # PA2082-1. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

CXCR6

Uniprot ID :

Q9EQ16

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bonzo (331-351aa EDSSKTCSASHNVETTSMFQL), different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

C-X-C chemokine receptor type 6

Synonyms :

C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CD186; Cxcr6;

Protein Name :

C-X-C chemokine receptor type 6

Molecular Weight :

40468 MW

Protein Function :

Receptor for the C-X-C chemokine CXCL16.

Subcellular Localization :

Cell membrane; Multi-pass membrane protein.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Background :

CXCR6 (Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al. (1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al. (2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al. (2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.

Research Category :

Antiviral Signaling, Host Virus Interaction, Immune System Diseases, Immunology, Interspecies Interaction, Microbiology