Anti-Claudin 6/CLDN6 Antibody | Boster PA2020 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Claudin 6/CLDN6 Antibody

catalog :

PA2020

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

sku :

PA2020

status :

Enabled

name :

Anti-Claudin 6/CLDN6 Antibody

category name :

Primary Antibodies, Polyclonal Antibodies

gene name :

CLDN6

price various sizes :

30ug sample size / $99 100ug / $240 100ug+Free HRP Secondary BA1054 / $240 100ug+Free Biotin Secondary BA1003 / $240

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

description :

Polyclonal antibody for Claudin 6/CLDN6 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. Claudin 6/CLDN6 information: Molecular Weight: 23292 MW; Subcellular Localization: Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein ; Tissue Specificity: Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.

short description :

Rabbit IgG polyclonal antibody for Claudin-6(CLDN6) detection. Tested with WB in Human.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

P56747

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 6(204-220aa APAISRGPSEYPTKNYV).

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Western blot, 0.1-0.5ug/ml, Human.

applications :

reactivity :

Human

image labels :

Anti-Claudin 6 antibody, PA2020, Western blotting. Lane 1: HELA Cell Lysate. Lane 2: SMMC Cell Lysate.

background :

Claudin-6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

competitor equivalent skus :

sc 242119 sc 242118

research category :

Cell Adhesion, Cytoskeleton / Ecm, Developmental Biology, Host Virus Interaction, Interspecies Interaction, Lineage Markers, Lineage Specification, Microbiology, Signal Transduction, Stem Cells, Tight Junctions

synonyms :

Claudin-6;Skullin;CLDN6;UNQ757/PRO1488;

gene full name :

Claudin-6

molecular weight :

23292 MW

protein function :

Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity). May act as a coreceptor for HCV entry into hepatic cells.

subcellular localization :

Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .

tissue specificity :

Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.

protein name :

Claudin-6

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

sequence similarities :

Belongs to the claudin family.

last modified :

1/28/19 19:39