Anti-Syndecan 2/SDC2 Antibody | Boster PA1896 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Syndecan 2/SDC2 Antibody

catalog :

PA1896

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

PA1896

status :

Enabled

name :

Anti-Syndecan 2/SDC2 Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

SDC2

price various sizes :

30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

description :

Polyclonal antibody for Syndecan 2/SDC2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. Syndecan 2/SDC2 information: Molecular Weight: 22160 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein.

short description :

Rabbit IgG polyclonal antibody for Syndecan-2(SDC2) detection. Tested with WB, IHC-P, IHC-F in Human.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

P34741

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human Syndecan 2(105-122aa EETDKEKVHLSDSERKMD).

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat . Immunohistochemistry(Frozen Section), 0.5-1ug/ml, Human, -. Western blot, 0.1-0.5ug/ml, Human.

applications :

IHC, WB

reactivity :

Human

image labels :

Anti-Syndecan 2 antibody, PA1896, IHC(P). IHC(P): Human Liver Cancer Tissue Anti-Syndecan 2 antibody, PA1896, Western blotting. Lane 1: HEPG Cell Lysate. Lane 2: A549 Cell Lysate. Lane 3: U87 Cell Lysate. Lane 4: SKOV Cell ysate. Lane 5: JURKAT Cell Lysate. Anti-Syndecan 2 antibody, PA1896, IHC(F). IHC(F): Human Placenta Tissue

background :

SDC2(Syndecan-2) also known as SYND2, HSPG1, HSPG, and Fibroglycan, is a protein that in humans is encoded by the SDC2 gene. The protein encoded by this gene is a transmembrane(type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. By Southern hybridization to a panel of human-mouse somatic cell hybrid DNA and by in situ hybridization, Marynen et al.(1989) showed that the heparan sulfate proteoglycan core protein maps to 8q22-q24.(Heparan sulfate proteoglycan of basement membrane appears to be encoded by a gene on human chromosome 1.Bobardt et al.(2003) demonstrated that syndecans, including SDC2, can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparan sulfate chains. Flow cytometric analysis demonstrated SDC expression on endothelial cells. HIV bound to SDC on endothelial cell lines maintained its infectivity for at least 1 week, compared with less than 1 day for unbound virus. Bobardt et al.(2003) suggested that SDC-rich endothelial cells lining the vasculature can provide a microenvironment that boosts HIV replication in T cells.

competitor equivalent skus :

sc 27493 sc 367285 sc 27494

research category :

Angiogenesis, Cardiovascular, Cell Adhesion Proteins, Cytoskeleton / Ecm, Ecm Proteins, Growth Factors, Neuroscience, Signal Transduction

synonyms :

Syndecan-2;SYND2;Fibroglycan;Heparan sulfate proteoglycan core protein;HSPG;CD362;SDC2;HSPG1;

gene full name :

Syndecan-2

molecular weight :

22160 MW

protein function :

Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).

subcellular localization :

Membrane; Single-pass type I membrane protein.

protein name :

Syndecan-2

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and IHC(F).

sequence similarities :

Belongs to the syndecan proteoglycan family.

last modified :

1/28/19 19:39