Anti-Flavin containing monooxygenase 4/FMO4 Antibody | Boster PA1883 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Flavin containing monooxygenase 4/FMO4 Antibody

catalog :

PA1883

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

PA1883

Product Name :

Anti-Flavin containing monooxygenase 4/FMO4 Antibody

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Rat, Human, By Heat. Western blot, 0.1-0.5µg/ml, Human, Mouse, Rat.

Application Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Flavin containing monooxygenase 4/FMO4 Antibody catalog # PA1883. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

FMO4

Uniprot ID :

P31512

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human Flavin containing monooxygenase 4 (75-92aa HEDYPNFMNHEKFWDYLQ), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Dimethylaniline monooxygenase [N-oxide-forming] 4

Synonyms :

Dimethylaniline monooxygenase [N-oxide-forming] 4; 1.14.13.8; Dimethylaniline oxidase 4; Hepatic flavin-containing monooxygenase 4; FMO 4; FMO4; FMO2;

Protein Name :

Dimethylaniline monooxygenase [N-oxide-forming] 4

Molecular Weight :

63343 MW

Protein Function :

This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.

Subcellular Localization :

Microsome membrane. Endoplasmic reticulum membrane.

Tissue Specificity :

Liver

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Sequence Similarities :

Belongs to the FMO family.

Background :

FMO4 (Flavin-containing monooxygenase 4) also known as FMO2, FORMERLY or FMO, ADULT LIVER FORM, is an enzyme that in humans is encoded by the FMO4 gene. By PCR analysis, Dolphin et al. (1992) mapped the FMO4 gene to chromosome 1. Southern blot hybridization with single exon probes demonstrated that human FMO4 and FMO1 are, in each case, the product of a single gene. Lawton et al. (1994) proposed a reclassification of mammalian FMOs. Under this system, FMO2 described by Dolphin et al. (1992) is now designated FMO4.

Research Category :

Drug Metabolism, Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Signal Transduction