Anti-Beta Actin Antibody | Boster PA1872 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Beta Actin Antibody

catalog :

PA1872

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

sku :

PA1872

name :

Anti-Beta Actin Antibody

price :

200 USD

immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human beta Actin(2-19aaDDDIAALVVDNGSGMCKA), identical to the related rat and mouse sequences.

form :

Lyophilized

host :

Rabbit

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

purification :

Immunogen affinity purified.

clonality :

Polyclonal

description :

Rabbit IgG polyclonal antibody for Actin, cytoplasmic 1(ACTB) detection. Tested with WB in Human;Mouse;Rat.

size :

100 ug/vial

reactivity :

Human; Mouse; Rat

applications :

background :

beta-Actin(ACTB) also known as BETA-ACTIN or ACTIN, CYTOPLASMIC, 1,Â is one of six differentÂ actinÂ isoforms which have been identified in humans. This is one of the two nonmuscleÂ cytoskeletalÂ actins. Actins are highly conserved proteinsÂ that are involved in cell motility, structure and integrity.Â Ueyama et al.(1996)Â used fluorescence in situ hybridization to map ACTB to 7p22. By PCR of somatic cell hybrid DNAs, they mapped 4 ACTB pseudogenes to other chromosomes. Karakozova et al.(2006)Â found that arginylation of beta-actin regulates cell motility. The majority of Ate1-null cells appeared smaller than wildtype cells and were apparently unable to form a lamella during movement along the substrate.Â Karakozova et al.(2006)Â concluded that arginylation of beta-actin apparently represents a critical step in the actin N-terminal processing needed for actin functioning in vivo.

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

cross reactivity :

No cross reactivity with other proteins

gene full name :

Actin, cytoplasmic 1

gene name :

ACTB

predicted reactivity :

Hamster

protein function :

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

protein name :

Actin, cytoplasmic 1

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

research category :

signal transduction cytoskeleton / ecm cytoskeleton microfilaments actin etc actin

sequence similarities :

Belongs to the actin family.

storage :

At -20ËšC for one year. After reconstitution, at 4ËšC for one month. It can also be aliquotted and stored frozen at -20ËšC for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Cytoplasm, cytoskeleton . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

synonyms :

Actin, cytoplasmic 1;Beta-actin;Actin, cytoplasmic 1, N-terminally processed;ACTB;

uniprot id :

P60709