Anti-Heat shock factor protein 1 HSF1 Antibody | Boster PA1606 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Heat shock factor protein 1 HSF1 Antibody

catalog :

PA1606

quantity :

10 ug sample

price :

99 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

product information

sku :

PA1606

status :

name :

Anti-Heat shock factor protein 1 HSF1 Antibody

url key :

anti-hsf1-antibody-pa1606-boster

product category :

Primary Antibodies

gene name :

HSF1

price :

315

size 1 :

10 ug sample

price for size 1 :

99 USD

size 2 :

Full size

price for size 2 :

315

size 3 :

Full size carrier free

price for size 3 :

365

clonality :

Polyclonal

concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 Œºg/ml.

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

description :

Boster Bio Anti-Heat shock factor protein 1 HSF1 Antibody catalog # PA1606. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

short description :

Boster Bio Anti-Heat shock factor protein 1 HSF1 Antibody catalog # PA1606. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

size :

100Œºg/vial

uniprot id :

Q00613

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human HSF1 (380-397aa DKNELSDHLDAMDSNLDN), identical to the related rat and mouse sequences.

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

Store at -20ÀöC for one year from date of receipt. After reconstitution, at 4ÀöC for one month. It can also be aliquotted and stored frozen at -20ÀöC for six months. Avoid repeated freeze-thaw cycles.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Immunocytochemistry , 0.5-1ug/ml, Human, Mouse, Rat. Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Rat, Human, Mouse . Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat. Western blot, 0.1-0.5ug/ml, Human, Rat, Mouse.

applications :

IHC,ICC,WB

reactivity :

Rat,Mouse,Human

predicted reactivity :

Hamster

images :

/antibody/pa1606-1-WB-anti-hsf1-antibody.jpg /antibody/pa1606-2-IHC-anti-hsf1-antibody.jpg

image labels :

Anti-HSF1 antibody PA1606 Western blotting. Lane 1: HELA Cell Lysate. Lane 2: 293T Cell Lysate. Lane 3: RAJI Cell Lysate. Lane 4: A549 Cell Lysate. Lane 5: MCF-7 Cell Lysate. Anti-HSF1 antibody PA1606 IHC(P). IHC(P): Human Mammary Cancer Tissue.

custom options :

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created at :

4/9/14 15:18

updated at :

3/2/22 2:54

meta title :

HSF1 Antibody (PA1606)

meta keyword :

Anti-Heat shock factor protein 1 HSF1 Antibody

meta description :

Boster Bio Anti-Heat shock factor protein 1 HSF1 Antibody catalog # PA1606. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100ug/vial in Lyophilized form antibody.

application notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

rating value :

100

background :

HSF1 (HEAT-SHOCK TRANSCRIPTION FACTOR 1), also called HEAT-SHOCK FACTOR 1, is a protein that in humans is encoded by the HSF1 gene. The product of HSF1 gene is a heat-shock transcription factor. The International Radiation Hybrid Mapping Consortium maps the HSF1 gene to chromosome 8. HSF1 exists as an inactive monomer in a complex with Hsp40/Hsp70 and Hsp90. Upon stress, such as elevated temperature, HSF1 is released from the chaperone complex and trimerizes. HSF1 is then transported into the nucleus where it is hyperphosphorylated and binds to DNA containing heat shock elements. HSF1's target genes include major inducible heat shock proteins such as Hsp72, and interestingly, noncoding RNA within Satellite III repeat regions. In a novel in vitro system human HSF1 can be activated by nonnative protein, heat, and geldanamycin. HSR1 is constitutively expressed in human and rodent cells and its homologs are functionally interchangeable. Furthermore, Hsf1-deficient mice had a longer free-running period than wildtype littermates.

competitor equivalent skus :

sc 9144 sc 17757 sc 17756 sc 8061 sc 13516 sc 393509 sc 393677 sc 9144 X sc 17757 X sc 393509 X sc 17756 X sc 8061 X sc 393677 X sc 13516 X

research category :

Cardiogenesis,Cardiovascular,Epigenetics And Nuclear Signaling,Nucleus,Subcellular Markers,Tags & Cell Markers,Transcription,Transcription Factors/Regulators

synonyms :

Heat shock factor protein 1;HSF 1;Heat shock transcription factor 1;HSTF 1;HSF1;HSTF1;

gene full name :

Heat shock factor protein 1

molecular weight :

57260 MW

protein function :

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

subcellular localization :

Cytoplasm. Nucleus. Cytoplasmic during normal growth. On activation, translocates to nuclear stress granules. Colocalizes with SUMO1 in nuclear stress granules.

protein name :

Heat shock factor protein 1(HSF 1)

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.

template :

antibodies