Anti-C-terminal-binding protein 2 CTBP2 Antibody | Boster PA1554 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-C-terminal-binding protein 2 CTBP2 Antibody

catalog :

PA1554

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

SKU :

PA1554

Product Name :

Anti-C-terminal-binding protein 2 CTBP2 Antibody

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Predicted Reactivity :

Chicken

Application(s) :

IHC-P, IHC-F, ICC, WB

Application Details :

Immunocytochemistry , 0.5-1µg/ml, HumanImmunohistochemistry (Frozen Section), 0.5-1µg/ml, Mouse, Rat, HumanImmunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, Mouse, Rat, By Heat. Western blot, 0.1-0.5µg/ml, Human, Rat, Mouse.

Application Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-C-terminal-binding protein 2 CTBP2 Antibody catalog # PA1554. Tested in IHC-P, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

CTBP2

Uniprot ID :

P56545

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human CTBP2 (429-445aa PNQPTKHGDNREHPNEQ), identical to the related rat and mouse sequences.

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

C-terminal-binding protein 2

Synonyms :

C-terminal-binding protein 2; CtBP2; CTBP2;

Protein Name :

C-terminal-binding protein 2(CtBP2)

Molecular Weight :

48945 MW

Protein Function :

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).

Subcellular Localization :

Nucleus. Cell junction, synapse.

Tissue Specificity :

Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.

Background :

The E1a region of group C adenoviruses encodes 2 nearly identical proteins that are largely responsible for the oncogenic properties of adenoviruses. The CTBP1 protein binds to the C-terminal half of these E1A proteins. It's predicted that CTBP2 is a 445-amino acid protein and it is 72% identical to CTBP1. The CTBP2 gene is mapped to chromosome 10q26.13. CTBP2 is a mammalian corepressor that targets diverse transcriptional regulators. It bounds the short medial portion of delta-EF1 containing the PLDLSL motif and it enhances transrepression activity of delta-EF1.

Research Category :

Cell Type Marker, Co-Factors, Epigenetics and Nuclear Signaling, Microbiology, Neuron Marker, Neuroscience, Synapse Marker, Transcription