Anti-Eotaxin/CCL11 Antibody | Boster PA1527-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Eotaxin/CCL11 Antibody

catalog :

PA1527-1

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

sku :

PA1527-1

status :

Enabled

name :

Anti-Eotaxin/CCL11 Antibody

category name :

Primary Antibodies, Polyclonal Antibodies

gene name :

CCL11

price various sizes :

30ug sample size / $99 100ug / $240 100ug+Free HRP Secondary BA1054 / $240 100ug+Free Biotin Secondary BA1003 / $240

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

description :

Polyclonal antibody for Eotaxin/CCL11 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. Eotaxin/CCL11 information: Molecular Weight: 10732 MW; Subcellular Localization: Secreted.

short description :

Rabbit IgG polyclonal antibody for Eotaxin(CCL11) detection. Tested with WB in Human.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

P51671

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Eotaxin(73-92aa CADPKKKWVQDSMKYLDQKS).

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Western blot, 0.1-0.5ug/ml, Human.

applications :

reactivity :

Human

image labels :

Anti- Eotaxin antibody, PA1527-1, Western blotting. All lanes: Anti Eotaxin(PA1527-1) at 0.5ug/ml. Lane 1: HELA Whole Cell Lysate at 40ug. Lane 2: MCF-7 Whole Cell Lysate at 40ug. Predicted bind size: 11KD. Observed bind size: 11KD

background :

Eotaxin, also known as CCL11(Chemokine(C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses.The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1(CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.

competitor equivalent skus :

sc 28971 sc 373764 sc 373767 sc 374233 sc 377082 sc 6181 sc 6182

research category :

Chemokines, Immunology, Innate Immunity

synonyms :

Eotaxin;C-C motif chemokine 11;Eosinophil chemotactic protein;Small-inducible cytokine A11;CCL11;SCYA11;

gene full name :

Eotaxin

molecular weight :

10732 MW

protein function :

In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.

subcellular localization :

Secreted.

protein name :

Eotaxin

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

sequence similarities :

Belongs to the intercrine beta (chemokine CC) family.

last modified :

1/28/19 19:39