Anti-OPN Antibody | Boster PA1432 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-OPN Antibody

catalog :

PA1432

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry - paraffin section

product information

sku :

PA1432

name :

Anti-OPN Antibody

price :

200 USD

immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of mouse SPP1(268-285aa DPKSKEDDRYLKFRISHE), identical to the related rat sequence.

form :

Lyophilized

host :

Rabbit

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

purification :

Immunogen affinity purified.

clonality :

Polyclonal

description :

Rabbit IgG polyclonal antibody for Osteopontin(SPP1) detection. Tested with WB, IHC-P in Mouse;Rat.

size :

100 ug/vial

reactivity :

Mouse; Rat

applications :

IHC-P; WB

background :

Osteopontin(OPN) also called urinary stone protein, secreted phosphoprotein 1(SPP1), bone sialoprotein, and early T lymphocyte activation 1(ETA1). Osteopontin is a phosphorylated glycoprotein secreted to the mineralizing extrOPNllular matrix by osteoblasts during bone development. Osteopontin is presumably involved in stone formation as stone matrix. The deduced protein sequence reveals a 317-amino acid protein(34,982 Da) containing a 16-amino acid hydrophobic signal sequence and a 33,352-Da protein destines to undergo extensive post-translational modifications before being secreted from the cell. The gene is located on human chromosome 4. The standard product used in this kit is recombinant human OPN, consisting of 17-314 amino acid sequence with the molecular mass of 32.9KDa. As a result of glycosylation, the molecular mass is 60-65KDa.

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

cross reactivity :

No cross reactivity with other proteins

gene full name :

Osteopontin

gene name :

SPP1; Spp1

protein function :

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.

protein name :

Osteopontin

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

research category :

cardiovascular angiogenesis adhesion / ecm extracellular matrix signal transduction cytoskeleton / ecm structures bone stem cells mesenchymal stem cells osteogenesis cancer tumor biomarkers

sequence similarities :

Belongs to the osteopontin family.

storage :

At -20ËšC for one year. After reconstitution, at 4ËšC for one month. It can also be aliquotted and stored frozen at -20ËšC for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Secreted.

synonyms :

Osteopontin;2AR;Bone sialoprotein 1;Calcium oxalate crystal growth inhibitor protein;Early T-lymphocyte activation 1 protein;Minopontin;Secreted phosphoprotein 1;SPP-1;Spp1;Eta-1, Op, Spp-1;

uniprot id :

P10923