Anti-SFTPA1 Antibody | Boster PA1347 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-SFTPA1 Antibody

catalog :

PA1347

quantity :

100μg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot

product information

SKU :

PA1347

Product Name :

Anti-SFTPA1 Antibody

Size :

100μg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Rat

Predicted Reactivity :

Hamster

Application(s) :

Application Details :

Western blot, 0.1-0.5µg/ml, Human, Rat.

Application Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-SFTPA1 Antibody catalog # PA1347. Tested in WB applications. This antibody reacts with Human, Rat.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

SFTPA1

Uniprot ID :

Q8IWL2

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1 (221-236aa KEQCVEMYTDGQWNDR), different from the rat sequence by two amino acids.

Form :

Liquid

Contents :

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins

Storage :

At -20˚C for one year and at 4˚C for one month from date of receipt. Avoid repeated freezing and thawing.

Gene Full Name :

Pulmonary surfactant-associated protein A1

Synonyms :

Pulmonary surfactant-associated protein A1; PSP-A; PSPA; SP-A; SP-A1; 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; Collectin-4; SFTPA1; COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B;

Protein Name :

Pulmonary surfactant-associated protein A1(PSP-A/PSPA/SP-A/SP-A1)

Molecular Weight :

26242 MW

Protein Function :

In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Sequence Similarities :

Belongs to the SFTPA family.

Background :

Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14.1. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

Research Category :

Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Signal Transduction