Anti-Glucose Transporter GLUT1/SLC2A1 Antibody | Boster PA1120-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Glucose Transporter GLUT1/SLC2A1 Antibody

catalog :

PA1120-1

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

sku :

PA1120-1

status :

Enabled

name :

Anti-Glucose Transporter GLUT1/SLC2A1 Antibody

category name :

Polyclonal Antibodies

gene name :

SLC2A1

price various sizes :

30ug sample size / $99 100ug / $240 100ug+Free HRP Secondary BA1054 / $240 100ug+Free Biotin Secondary BA1003 / $240

clonality :

Polyclonal

concentration :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

conjugate :

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

description :

Polyclonal antibody for Glut1/SLC2A1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. Glut1/SLC2A1 information: Molecular Weight: 54084 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein. Melanosome. Localizes primarily at the cell surface. Identified by mass spectrometry in melanosome fractions from stage I to stage IV; Tissue Specificity: Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.

short description :

Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 1(SLC2A1) detection. Tested with WB in Human;Mouse;Rat.

size :

100 ug/vial

sample size available :

30ug for $99, contact us for details

uniprot id :

P11166

host :

Rabbit

immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A1(477-492aa KTPEELFHPLGADSQV), identical to the related mouse and rat sequences.

form :

Lyophilized

purification :

Immunogen affinity purified.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

cross reactivity :

No cross reactivity with other proteins

reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

application details :

Western blot, 0.1-0.5ug/ml, Human, Rat, Mouse.

applications :

reactivity :

Human, Mouse, Rat

predicted reactivity :

Hamster

image labels :

Anti-SLC2A1 antibody, PA1120-1, Western blotting. All lanes: Anti SLC2A1(PA1120-1) at 0.5ug/ml. Lane 1: Rat Liver Tissue Lysate at 50ug. Lane 2: SW620 Whole Cell Lysate at 40ug. Lane 3: 293T Whole Cell Lysate at 40ug. Predicted bind size: 57KD. Observed bind size: 57KD

background :

GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid(the oxidized form of vitamin C) into the brain1, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.

competitor equivalent skus :

sc 79103 sc 79102 sc 79100 sc 98362 sc 377405 sc 81383 sc 514232

research category :

Channels, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Plasma Membrane, Signal Transduction

synonyms :

Solute carrier family 2, facilitated glucose transporter member 1;Glucose transporter type 1, erythrocyte/brain;GLUT-1;HepG2 glucose transporter;SLC2A1;GLUT1;

gene full name :

Solute carrier family 2, facilitated glucose transporter member 1

molecular weight :

54084 MW

protein function :

Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.

subcellular localization :

Cell membrane; Multi-pass membrane protein. Melanosome. Localizes primarily at the cell surface. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

tissue specificity :

Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.

protein name :

Solute carrier family 2, facilitated glucose transporter member 1

recommended detection systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

sequence similarities :

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

last modified :

1/28/19 19:39