Anti-Phospho-Histone H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM194

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-Histone H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM194

catalog :

P14495

quantity :

100 ug

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM194

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry

product information

sku :

P14495

status :

Enabled

name :

Anti-Phospho-Histone H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM194

category name :

Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

HIST1H4A

clonality :

Monoclonal

clone number :

RM194

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

description :

Anti-Phospho-Histone H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM194 tested in WB, ELISA, Multiplex, ICC, reactive to All Vertebrates

short description :

Anti-Phospho-Histone H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM194 tested in WB, ELISA, Multiplex, ICC, reactive to All Vertebrates

size :

100 ug

uniprot id :

P62805

host :

Rabbit

immunogen :

A phospho-peptide corresponding to the Phospho-Histone H4 (pSer1).

storage :

-20 C

applications :

ELISA, ICC, WB

reactivity :

Human, Mouse, Rat

image labels :

Figure 1. Specificity Test result. RM194 specifically reacts to Histone H4 phosphorylated at Serine 1 (H4S1p). The reactivity is not affected by neighboring Arginine 3 modifications (H4S1pR3me1 and H4S1pR3me2). No cross reactivity with Histone H2A phosphorylated at Serine 1 (H2AS1p). Figure 2. ICC result. Immunocytochemistry of HeLa cells, using Anti-Phospho-Histone H4 (Ser1) Rabbit mAb RM194 (red). Actin filaments have been labeled with fluorescein phalloidin (green). Figure 3. ICC result. Immunocytochemistry of HeLa cells, using Anti-Phospho-Histone H4 (Ser1) Rabbit mAb RM194 (red). Actin filaments have been labeled with fluorescein phalloidin (green).

research category :

Epigenetics And Nuclear Signaling, Histones, Unmodified

synonyms :

Histone H4;HIST1H4A;H4/A, H4FA;HIST1H4B;H4/I, H4FI;HIST1H4C;H4/G, H4FG;HIST1H4D;H4/B, H4FB;HIST1H4E;H4/J, H4FJ;HIST1H4F;H4/C, H4FC;HIST1H4H;H4/H, H4FH;HIST1H4I;H4/M, H4FM;HIST1H4J;H4/E, H4FE;HIST1H4K;H4/D, H4FD;HIST1H4L;H4/K, H4FK;HIST2H4A;H4/N, H4F2, H4FN, HIST2H4;HIST2H4B;H4/O, H4FO;HIST4H4;

gene full name :

Histone H4

molecular weight :

11367 MW

protein function :

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

subcellular localization :

Nucleus. Chromosome.

last modified :

2/6/19 22:57