Anti-Phospho-MLK3 (Ser674) Polyclonal Antibody | Boster P04412 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-MLK3 (Ser674) Polyclonal Antibody

catalog :

P04412

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

sku :

P04412

status :

Enabled

name :

Anti-Phospho-MLK3 (Ser674) Polyclonal Antibody

category name :

Primary Antibodies, Polyclonal Antibodies

gene name :

MAP3K11

price various sizes :

5ul sample size / $40 100ul / $299 100ul+Free HRP Secondary BA1054 / $299 100ul+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

description :

Polyclonal antibody for MAP3K11 detection. Host: Rabbit.Size: 100ul. Tested applications: WB. Reactive species: Human. MAP3K11 information: Molecular Weight: 92688 MW; Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent; Tissue Specificity: Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain.

short description :

Rabbit Polyclonal Antibody for Phospho-MLK3 (Ser674) (MAP3K11) detection. Tested with WB in Human, Mouse, Rat.

size :

100 ul

sample size available :

5ul, free with shipping charge

uniprot id :

Q16584

host :

Rabbit

immunogen :

Synthesized peptide derived from human MLK3 around the phosphorylation site of S674.

form :

Liquid

purification :

Immunogen affinity purified

storage :

Store at -20 C for one year, at 4 C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20 C upon receiving. Avoid repeated freezing and thawing.

application details :

WB, 1:500-1:2000.

applications :

reactivity :

Human, Mouse, Rat

image labels :

Western Blot analysis of NIH-3T3, cells using Phospho-MLK3 (S674) Polyclonal antibody

research category :

Protein Phosphorylation, Ser / Thr Kinases, Signal Transduction, Tyrosine Kinases

synonyms :

Mitogen-activated protein kinase kinase kinase 11;2.7.11.25;Mixed lineage kinase 3;Src-homology 3 domain-containing proline-rich kinase;MAP3K11 ;MLK3 , PTK1, SPRK ;

gene full name :

Mitogen-activated protein kinase kinase kinase 11

molecular weight :

92688 MW

protein function :

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

subcellular localization :

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.

tissue specificity :

Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain.

last modified :

2/6/19 22:57