Anti-Acetylated eIF5A (Lys47) Antibody | Boster P01727 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Acetylated eIF5A (Lys47) Antibody

catalog :

P01727

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

sku :

P01727

status :

Enabled

name :

Anti-Acetylated eIF5A (Lys47) Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

EIF5A

price various sizes :

100ug / $299 100ug+Free HRP Secondary BA1054 / $299 100ug+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

description :

Polyclonal antibody for EIF5A detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. EIF5A information: Molecular Weight: 16832 MW; Subcellular Localization: Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions; Tissue Specificity: Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level).

short description :

Anti-Acetylated eIF5A (Lys47) Antibody

size :

100 ug/vial

uniprot id :

P63241

host :

Rabbit

immunogen :

A Acetyl-peptide derived from human eIF5A around the Acetylation site of Lys47.

form :

Liquid

purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.

storage :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

application details :

User need to optimize the dilution ratio for this antibody

applications :

reactivity :

Human, Mouse, Rat

image labels :

Western blot analysis of lysate from L929 cells, using eIF5A (Acetyl-Lys47) Antibody.

competitor equivalent skus :

sc 18938 sc 366096 sc 390062 sc 390202 sc 18939

research category :

Dna / Rna, Epigenetics And Nuclear Signaling, Rna Processing, Translation

synonyms :

Eukaryotic translation initiation factor 5A-1;eIF-5A-1;eIF-5A1;Eukaryotic initiation factor 5A isoform 1;eIF-5A;Rev-binding factor;eIF-4D;EIF5A;

gene full name :

Eukaryotic translation initiation factor 5A-1

molecular weight :

16832 MW

protein function :

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF- alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

subcellular localization :

Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.

tissue specificity :

Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level).

last modified :

2/6/19 22:57