Anti-Phospho-c-Met Y1349/Y1356 Antibody | Boster P01488 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-c-Met Y1349/Y1356 Antibody

catalog :

P01488

quantity :

100 uL

price :

339 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

sku :

P01488

name :

Anti-Phospho-c-Met Y1349/Y1356 Antibody

price :

339 USD

form :

Liquid

host :

Rabbit

clonality :

Polyclonal

description :

Anti-c-Met phospho Y1349 / Y1356 Antibody validated for WB in Human.

size :

100 uL

reactivity :

Human; Mouse; Rat

applications :

background :

c-Met, also called MET and hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. It is mapped to 7q31.2. The protein possesses tyrosine kinase activity. MET is a membrane receptor that is essential for embryonic development and wound healing. It induces several biological responses that collectively give rise to a program known as invasive growth. MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. Normally, only stem cells and progenitor cells express MET, which allows these cells to grow invasively in order to generate new tissues in an embryo or regenerate damaged tissues in an adult. However, cancer stem cells are thought to hijack the ability of normal stem cells to express MET, and thus become the cause of cancer persistence and spread to other sites in the body.

concentration :

1.01 mg/mL by UV absorbance at 280 nm

gene name :

Met

synonyms :

Met protein ;Met ;

uniprot id :

A4FUV6