Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM216

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM216

catalog :

P00241

quantity :

100 ug

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM216

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry

product information

sku :

P00241

status :

Enabled

name :

Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM216

category name :

Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

H2AFX

clonality :

Monoclonal

clone number :

RM216

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

description :

Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM216 tested in WB, ELISA, Multiplex, ICC, reactive to All Vertebrates

short description :

Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit Monoclonal Antibody, Clone#RM216 tested in WB, ELISA, Multiplex, ICC, reactive to All Vertebrates

size :

100 ug

uniprot id :

P16104

host :

Rabbit

immunogen :

An unmodified peptide corresponding to the N-terminus of Histone H3.

storage :

-20 C

applications :

ELISA, ICC, WB

reactivity :

Human, Mouse, Rat

image labels :

Figure 1. ICC result. Immunocytochemistry of HeLa cells, using Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit mAb RM216 (red). Actin filaments have been labeled with fluorescein phalloidin (green). Figure 2. ICC result. Immunocytochemistry of HeLa cells, using Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit mAb RM216 (red). Actin filaments have been labeled with fluorescein phalloidin (green). Figure 3. ICC result. Immunocytochemistry of HeLa cells, using Anti-Phospho-Histone H2A/H4 (Ser1) Rabbit mAb RM216 (red). Actin filaments have been labeled with fluorescein phalloidin (green).

research category :

Chip'Ing Antibodies, Dna / Rna, Dna Damage Response, Epigenetics And Nuclear Signaling, Histones

synonyms :

Histone H2AX;H2a/x;Histone H2A.X;H2AFX;H2AX;

gene full name :

Histone H2AX

molecular weight :

15145 MW

protein function :

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.

subcellular localization :

Nucleus . Chromosome .

last modified :

4/11/19 19:31