Anti-Gamma-Tubulin GGA3 Antibody (Monoclonal, GTU-88) | Boster MA1114 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Gamma-Tubulin GGA3 Antibody (Monoclonal, GTU-88)

catalog :

MA1114

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GTU-88

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

SKU :

MA1114

Product Name :

Anti-Gamma-Tubulin GGA3 Antibody (Monoclonal, GTU-88)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

GTU-88

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Predicted Reactivity :

Hamster

Application(s) :

ICC, WB

Application Details :

Immunocytochemistry , 1µg/mlµg/ml, Human, mouse, rat Western blot, 0.25-0.5µg/mlµg/ml, Human, mouse, rat.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Gamma-Tubulin GGA3 Antibody (Monoclonal, GTU-88) catalog # MA1114. Tested in ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

GGA1; GGA2; GGA3

Uniprot ID :

D3ZHG8

Immunogen :

Synthetic gamma-tubulin peptide (amino acids 38-53), conjugated to KLH.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

golgi-associated, gamma adaptin ear containing, ARF binding protein 1; golgi-associated, gamma adaptin ear containing, ARF binding protein 2; golgi-associated, gamma adaptin ear containing, ARF binding protein 3

Synonyms :

Golgi associated, gamma adaptin ear containing, ARF binding protein 3 (Predicted) ; Protein Gga3 ; Gga3 ; Gga3_predicted ; rCG_32821 ;

Protein Name :

ADP-ribosylation factor-binding protein GGA1; ADP-ribosylation factor-binding protein GGA2; ADP-ribosylation factor-binding protein GGA3

Molecular Weight :

71715 MW

Protein Function :

GGA1: Plays a role in protein sorting and trafficking betweenthe trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and bindsubiquitinated proteins and membrane cargo molecules with acytosolic acidic cluster-dileucine (AC-LL) motif. GGA2: Plays a role in protein sorting and trafficking betweenthe trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and bindsubiquitinated proteins and membrane cargo molecules with acytosolic acidic cluster-dileucine (AC-LL) motif. GGA3: Plays a role in protein sorting and trafficking betweenthe trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and bindsubiquitinated proteins and membrane cargo molecules with acytosolic acidic cluster-dileucine (AC-LL) motif.

Subcellular Localization :

GGA1: Golgi apparatus, trans-Golgi networkmembrane; Peripheral membrane protein. Endosome membrane;Peripheral membrane protein. Gga1: Golgi apparatus, trans-Golgi networkmembrane Endosome membrane GGA2: Golgi apparatus, trans-Golgi networkmembrane Gga2: Golgi apparatus, trans-Golgi networkmembrane Endosome membrane GGA3: Golgi apparatus, trans-Golgi networkmembrane Gga3: Golgi apparatus, trans-Golgi networkmembrane Endosome membrane

Tissue Specificity :

GGA1: Ubiquitously expressed.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for ICC.

Sequence Similarities :

Belongs to the GGA protein family.

Background :

Gamma-tubulin is a universal component of microtubule organizing centers, which is essential for nuclear division and microtubule assembly in Aspergillus nidulans. TUBG1 mapped to within 20 kb of TUBG2 at 17q21. Gamma-tubulin is a minor protein, present at less than 1% the level of alpha- and beta-tubulin, and is limited to the centrosome. Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens.

Research Category :

Golgi Proteins, Protein Trafficking, Signal Transduction