Anti-Beta-HCG CGB Antibody (Monoclonal, PC-2) | Boster MA1111 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Beta-HCG CGB Antibody (Monoclonal, PC-2)

catalog :

MA1111

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PC-2

The same clone is also sold as:

Abnova: MAB1536

reactivity :

human

application :

immunohistochemistry

product information

SKU :

MA1111

Product Name :

Anti-Beta-HCG CGB Antibody (Monoclonal, PC-2)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

PC-2

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 2µg/ml, Human, By Heat.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Beta-HCG CGB Antibody (Monoclonal, PC-2) catalog # MA1111. Tested in IHC applications. This antibody reacts with Human.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

CGB

Uniprot ID :

P01233

Immunogen :

Purified human Chorionic Gonadotropin.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

Cross-reactivities with LH, FSH and TSH are less than 0.3%.

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Choriogonadotropin subunit beta

Synonyms :

Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotrophin chain beta; CGB; CGB3; CGB5; CGB7; CGB8;

Protein Name :

Choriogonadotropin subunit beta

Molecular Weight :

17739 MW

Protein Function :

Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Subcellular Localization :

Secreted.

Tissue Specificity :

Placenta

Recommended Detection Systems :

Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Sequence Similarities :

Belongs to the glycoprotein hormones subunit beta family.

Background :

beta-HCG (beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain (CGB). It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.

Research Category :

Chromatin Remodeling, Co-Factors, Epigenetics and Nuclear Signaling, Transcription