Anti-Tyrosine Hydroxylase Antibody (Monoclonal, TH-16)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Tyrosine Hydroxylase Antibody (Monoclonal, TH-16)

catalog :

MA1100

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TH-16

The same clone is also sold as:

Abnova: MAB1533
Invitrogen: MA5-32984

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

SKU :

MA1100

Product Name :

Anti-Tyrosine Hydroxylase Antibody (Monoclonal, TH-16)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

TH-16

Host :

Mouse

Reactivity :

Human, Mouse, Rabbit, Rat

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, rat, rabbit, By Heat. Immunohistochemistry (Frozen Section), 0.5-1µg/ml, Human, rat, rabbit Western blot, 0.25-0.5µg/ml, Human, mouse, rat, rabbit.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Tyrosine Hydroxylase Antibody (Monoclonal, TH-16) catalog # MA1100. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rabbit, Rat.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

Uniprot ID :

P04177

Immunogen :

Rat tyrosine hydroxylase (TH).

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Tyrosine 3-monooxygenase

Synonyms :

Tyrosine 3-monooxygenase; 1.14.16.2; Tyrosine 3-hydroxylase; TH; Th;

Protein Name :

Tyrosine 3-monooxygenase

Molecular Weight :

55966 MW

Protein Function :

Plays an important role in the physiology of adrenergic neurons.

Tissue Specificity :

TH: Mainly expressed in the brain and adrenalglands.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).

Sequence Similarities :

Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

Background :

Tyrosine hydroxylase is involved in the conversion of phenylalanine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Human TH gene contains 13 primary exons and spans approximately 8 kb. TH is in the 11p15.5 region.

Research Category :

Cancer, Cancer Metabolism, Cell Type Marker, Endocrine Metabolism, Hormone Biosynthesis, Hypoxia, Metabolic Signaling Pathway, Metabolism, Metabolism Processes, Neuron Marker, Neuroscience, Neurotransmitter, Pathways And Processes, Response To Hypoxia