Anti-Synaptophysin Syp Antibody (Monoclonal, SVP-38) | Boster MA1091 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Synaptophysin Syp Antibody (Monoclonal, SVP-38)

catalog :

MA1091

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SVP-38

The same clone is also sold as:

Santa Cruz Biotechnology: sc-12737 HRP, sc-12737 AC, sc-12737
Abnova: MAB1527
MilliporeSigma: S5768

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

SKU :

MA1091

Product Name :

Anti-Synaptophysin Syp Antibody (Monoclonal, SVP-38)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

SVP-38

Host :

Mouse

Reactivity :

Human, Rat

Predicted Reactivity :

Monkey

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 1-2µg/ml, Human, rat, By Heat. Immunohistochemistry (Frozen Section), 1-2µg/ml, Human, rat Western blot, 0.5-1µg/ml, Human, rat.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Synaptophysin Syp Antibody (Monoclonal, SVP-38) catalog # MA1091. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

SYP

Uniprot ID :

P07825

Immunogen :

Rat retina synaptosome.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Synaptophysin

Synonyms :

Synaptophysin; Major synaptic vesicle protein p38; Syp;

Protein Name :

Synaptophysin

Molecular Weight :

33311 MW

Protein Function :

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).

Subcellular Localization :

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.

Tissue Specificity :

Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).

Sequence Similarities :

Belongs to the synaptophysin/synaptobrevin family.

Background :

Synaptophysin (SYP) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Ozcelik et al. (1990) concluded that the gene has 7 exons distributed over about 20 kb. SYP mapped the SYP locus to Xp11.23-p11.22. Regionalization of the gene on the X chromosome was also done with hamster/human hybrid cells in which various portions of the human X chromosome were present.