Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) | Boster MA1075 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100)

catalog :

MA1075

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DCS-100

The same clone is also sold as:

OriGene: AM05227PU-N
Abnova: MAB2027
Santa Cruz Biotechnology: sc-56334

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

MA1075

Product Name :

Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

DCS-100

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC, ICC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 1-2µg/ml, Human, By Heat. Immunocytochemistry, 1µg/ml, Human Western blot, 0.5-1µg/ml, Human.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) catalog # MA1075. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

CDKN2D

Uniprot ID :

Q60773

Immunogen :

Recombinant human p19INK4d.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Cyclin-dependent kinase 4 inhibitor D

Synonyms :

Cyclin-dependent kinase 4 inhibitor D; p19-INK4d; Cdkn2d;

Protein Name :

Cyclin-dependent kinase 4 inhibitor D

Molecular Weight :

17809 MW

Protein Function :

Interacts strongly with CDK4 and CDK6 and inhibits them.

Subcellular Localization :

Nucleus. Cytoplasm.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.

Sequence Similarities :

Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.

Background :

Cyclins are important in regulating the cell cycle through their formation of enzymatic complexes with various cyclin-dependent kinases. P19 (INK4d) also kowns as cyclin-dependent kinase inhibitor 2D, is one of the novel members of the mouse INK4 gene family. Okuda et al. (1995) described the cloning of the human INK4d gene (CDKN2D). The predicted 166-amino acid protein is 86% identical to the mouse protein and about 45% identical to other human INK4 family members.

Research Category :

Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Epigenetics and Nuclear Signaling, Oncoproteins/Suppressors, Tumor Suppressors