This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1)
catalog :
MA1061
quantity :
100μg/vial
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
45M1

The same clone is also sold as:
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry
product information
SKU :
MA1061
Product Name :
Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1)
Size :
100μg/vial
Clonality :
Monoclonal
Clone Number :
45M1
Host :
Mouse
Reactivity :
Human, Rabbit, Rat
Application(s) :
IHC, ICC, WB
Application Details :
Immunohistochemistry (Paraffin-embedded Section), 2-4µg/ml, Human, rabbit, rat, By Heat. Immunocytochemistry, 1µg/ml, Human, rabbit, rat Western blot, 1-2µg/ml, Human, rabbit, rat.
Application Notes :
Other applications have not been tested. Optimal dilutions should be determined by end users.
Description :
Boster Bio Anti-Mucin Gastric MUC5AC Antibody (Monoclonal, 45M1) catalog # MA1061. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Rabbit, Rat.
Concentration :
Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Gene Name :
MUC5B
Uniprot ID :
P98088
Immunogen :
Mucin from human ovarian cyst fluid.
Form :
Lyophilized
Contents :
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Purification :
Ascites
Cross-reactivity :
No cross reactivity with other proteins
Isotype :
Mouse IgG1
Storage :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution :
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Gene Full Name :
Mucin-5AC
Synonyms :
Mucin-5AC ; MUC-5AC ; Gastric mucin ; Lewis B blood group antigen ; LeB ; Major airway glycoprotein ; Mucin-5 subtype AC, tracheobronchial; Tracheobronchial mucin ; TBM ; MUC5AC ; MUC5 ;
Protein Name :
Mucin-5AC
Molecular Weight :
585570 MW
Protein Function :
Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
Subcellular Localization :
Secreted.
Tissue Specificity :
Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.
Sequence Similarities :
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Background :
Mucin 5AC (Muc5AC) is a protein that in humans is encoded by the MUC5AC gene. Using real-time RT-PCR, Moehle et al. (2006) found that MUC5AC was highly expressed in adult trachea and stomach. Expression was lower in adult lung and weak in fetal lung, and no expression was detected in other tissues. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease. Moreover, Muc5ac is identified as a direct and critical mediator of resistance during intestinal nematode infection.
Research Category :
Cancer, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction, Tumor Antigens, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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