Anti-Laminin LAMA1 Monoclonal Antibody | Boster MA1054 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Laminin LAMA1 Monoclonal Antibody

catalog :

MA1054

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LAM-89

The same clone is also sold as:

Abnova: MAB12452
MilliporeSigma: L8271

reactivity :

human, rat

application :

immunohistochemistry

product information

SKU :

MA1054

Product Name :

Anti-Laminin LAMA1 Monoclonal Antibody

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

LAM-89

Host :

Mouse

Reactivity :

Human, Pig

Application(s) :

IHC

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, feline, pig, By Heat.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Laminin LAMA1 Monoclonal Antibody catalog # MA1054. Tested in IHC applications. This antibody reacts with Human, Pig.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

LAMA1; LAMA2; LAMB1; LAMB2

Uniprot ID :

P15800

Immunogen :

Human laminin.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Laminin subunit beta-2

Synonyms :

Laminin subunit beta-2; Laminin chain B3; Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; S-laminin subunit beta; S-LAM beta; Lamb2;

Protein Name :

Laminin subunit alpha-1; Laminin subunit alpha-2; Laminin subunit beta-1; Laminin subunit beta-2

Molecular Weight :

196474 MW

Protein Function :

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix, basement membrane.

Tissue Specificity :

Found in the basement membranes (major component). S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Sequence Similarities :

Contains 17 laminin EGF-like domains.

Background :

Laminin is a heterotrimeric extracellular matrix protein consisting of 3 chains: alpha-1,beta-1 and gamma-1, formerly called beta-2 (LAMA2). This gene is over 260,000 base pairs and contains 64 exons. Laminin is similar with merosin, a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve, and both of them are members of the same family of basement membrane proteins. And merosin is the same as laminin M, a striated muscle-specific, basal-lamina-associated protein, it may play a primary role in the pathogenesis of that disorder.

Research Category :

Angiogenesis, Cardiovascular, Cell Adhesion Proteins, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Intermediate Filaments, Neuroscience, Signal Transduction