Anti-Insulin Ins2 Antibody (Monoclonal, K36AC10) | Boster MA1052 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Insulin Ins2 Antibody (Monoclonal, K36AC10)

catalog :

MA1052

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K36aC10

The same clone is also sold as:

MilliporeSigma: I2018
OriGene: DM234-05, DM234
Abnova: MAB1502

reactivity :

human, rat

application :

immunohistochemistry

product information

SKU :

MA1052

Product Name :

Anti-Insulin Ins2 Antibody (Monoclonal, K36AC10)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

K36AC10

Host :

Mouse

Reactivity :

Human, Rabbit, Rat

Application(s) :

IHC

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 0.4-1µg/ml, Human, rabbit, rat, By Heat.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Insulin Ins2 Antibody (Monoclonal, K36AC10) catalog # MA1052. Tested in IHC applications. This antibody reacts with Human, Rabbit, Rat.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

INS

Uniprot ID :

P01323

Immunogen :

Human insulin.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Insulin-2

Synonyms :

Insulin-2; Insulin-2 B chain; Insulin-2 A chain; Ins2; Ins-2;

Protein Name :

Insulin

Molecular Weight :

12339 MW

Protein Function :

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Subcellular Localization :

Secreted.

Recommended Detection Systems :

Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Sequence Similarities :

Belongs to the insulin family.

Background :

Insulin, synthesized by the beta cells of the islets of Langerhans, consists of 2 dissimilar polypeptide chains, A and B, which are linked by 2 disulfide bonds. The insulin gene contains 3 exons and 2 introns; exon 2 encodes the signal peptide, the B chain, and part of the C peptide, while exon 3 encodes the remainder of the C peptide and the A chain. Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Harper et al. (1981) and Harper and Saunders (1981) assigned the insulin gene to 11p15.5 by in situ hybridization.