Anti-GAP43 Antibody (Monoclonal, GAP-7B10) | Boster MA1042 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-GAP43 Antibody (Monoclonal, GAP-7B10)

catalog :

MA1042

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GAP-7B10

The same clone is also sold as:

Abnova: MAB1455

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

MA1042

Product Name :

Anti-GAP43 Antibody (Monoclonal, GAP-7B10)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

GAP-7B10

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 1-2µg/ml, Human, mouse, rat, By Heat. Immunohistochemistry (Frozen Section), 1-2µg/ml, Human, mouse, rat Western blot, 0.5-1µg/ml, Human, mouse, rat.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-GAP43 Antibody (Monoclonal, GAP-7B10) catalog # MA1042. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

GAP43

Uniprot ID :

P07936

Immunogen :

GAP-43 from neonatal rat forebrain membranes.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG2a

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Neuromodulin

Synonyms :

Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Protein F1; Gap43;

Protein Name :

Neuromodulin

Molecular Weight :

23603 MW

Protein Function :

This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity).

Subcellular Localization :

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane ; Peripheral membrane protein. Cytoplasmic surface of growth cone and synaptic plasma membranes.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).

Sequence Similarities :

Belongs to the neuromodulin family.

Background :

GAP43 is expressed by developing and regenerating neurons, and to a lesser extent, reactive glial cells. It is used widely to specifically label injured neurons and to score neuronal regeneration. GAP43 is also a neuronal growth cone protein thought to be involved in pathfinding. GAP43 is considered to be a crucial component of an effective regenerative response in the nervous system.

Research Category :

Axonal Guidance Proteins, Cell Type Marker, Growth And Development, Neurology Process, Neuron Marker, Neuroscience, Synapse Marker