Anti-Elastin ELN Antibody (Monoclonal, BA-4) | Boster MA1038 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Elastin ELN Antibody (Monoclonal, BA-4)

catalog :

MA1038

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BA-4

The same clone is also sold as:

MilliporeSigma: E4013
Invitrogen: MA1-27129
Novus Biologicals: NB100-2076
Santa Cruz Biotechnology: sc-58756

reactivity :

human

application :

immunohistochemistry

product information

SKU :

MA1038

Product Name :

Anti-Elastin ELN Antibody (Monoclonal, BA-4)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

BA-4

Host :

Mouse

Reactivity :

Bovine, Human

Application(s) :

IHC

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 0.25-0.5µg/ml, Bovine, human, By Heat.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Elastin ELN Antibody (Monoclonal, BA-4) catalog # MA1038. Tested in IHC applications. This antibody reacts with Bovine, Human.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

ELN

Uniprot ID :

P15502

Immunogen :

Bovine alpha-elastin.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Elastin

Synonyms :

Elastin; Tropoelastin; ELN;

Protein Name :

Elastin

Molecular Weight :

68469 MW

Protein Function :

Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).

Subcellular Localization :

Secreted, extracellular space, extracellular matrix. Extracellular matrix of elastic fibers.

Tissue Specificity :

Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin.

Recommended Detection Systems :

Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Sequence Similarities :

Belongs to the elastin family.

Background :

Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.

Research Category :

Cardiovascular, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Signal Transduction, Vasculature