Anti-Desmin Antibody (Monoclonal, DE-U-10) | Boster MA1036 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Desmin Antibody (Monoclonal, DE-U-10)

catalog :

MA1036

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DE-U-10

The same clone is also sold as:

Invitrogen: MA1-22150, 14-9747-37, 50-9747-82, 14-9747-82, 50-9747-80, 14-9747-80
Abcam: ab6322
MilliporeSigma: D1033

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

MA1036

Product Name :

Anti-Desmin Antibody (Monoclonal, DE-U-10)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

DE-U-10

Host :

Mouse

Reactivity :

Human, Mouse, Rabbit, Rat

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 2-4µg/ml, Human, mouse, rat, rabbit, By Heat. Western blot, 2µg/ml, Human, mouse, rat, rabbit.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Desmin Antibody (Monoclonal, DE-U-10) catalog # MA1036. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rabbit, Rat.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

DES

Uniprot ID :

P48675

Immunogen :

Desmin from pig stomach.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Desmin

Synonyms :

Desmin; Des;

Protein Name :

Desmin

Molecular Weight :

53457 MW

Protein Function :

Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.

Subcellular Localization :

Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm. Cell membrane, sarcolemma. Localizes in the intercalated disks which occur at the Z line of cardiomyocytes.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Sequence Similarities :

Belongs to the intermediate filament family.

Background :

Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball (1992) found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al. (1989) localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy.

Research Category :

Complement, Immunology, Innate Immunity