Anti-CEACAM5/Cd66e Monoclonal Antibody | Boster MA1023 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CEACAM5/Cd66e Monoclonal Antibody

catalog :

MA1023

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

C6G9

The same clone is also sold as:

MilliporeSigma: C2331

reactivity :

human

application :

western blot, immunohistochemistry

product information

SKU :

MA1023

Product Name :

Anti-CEACAM5/Cd66e Monoclonal Antibody

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

C6G9

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 0.5-2µg/ml, Human, By Heat. Western blot, 0.5-1µg/ml, Human.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-CEACAM5/Cd66e Monoclonal Antibody catalog # MA1023. Tested in IHC, WB applications. This antibody reacts with Human.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

CEACAM1

Uniprot ID :

P06731

Immunogen :

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEA) isolated from a human colon adenocarcinoma cell line.

Form :

lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Carcinoembryonic antigen-related cell adhesion molecule 5

Synonyms :

Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e; CEACAM5

Protein Name :

Carcinoembryonic antigen-related cell adhesion molecule 5

Protein Function :

Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells

Subcellular Localization :

Cell membrane

Tissue Specificity :

Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Sequence Similarities :

Belongs to the immunoglobulin superfamily. CEA family.

Background :

Carcinoembryonic antigen is a complex immunoreactive glycoprotein with a molecular weight of 180,000 comprising 60% carbohydrate. It is found in adenocarcinomas of endodermally derived digestive system epithelia and in fetal colon.Carcinoembryonic antigen is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma.

Research Category :

Cancer, Cell Type Markers, Human Protein, Microbiology, Oncoproteins/Suppressors, Protein, Tags & Cell Markers, Tumor Antigens, Tumor Associated, Tumor Biomarkers, Tumor Immunology, Tumor Suppressors, Tumor-Associated Antigens