Anti-CDC25C Antibody (Monoclonal, DCS-193) | Boster MA1018 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CDC25C Antibody (Monoclonal, DCS-193)

catalog :

MA1018

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DCS-193

reactivity :

human, rat

application :

western blot

product information

SKU :

MA1018

Product Name :

Anti-CDC25C Antibody (Monoclonal, DCS-193)

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

DCS-193

Host :

Mouse

Reactivity :

Human

Application(s) :

Application Details :

Western blot, 1-2µg/ml, Human.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-CDC25C Antibody (Monoclonal, DCS-193) catalog # MA1018. Tested in WB applications. This antibody reacts with Human.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

CDC25C

Uniprot ID :

D4ADT2

Immunogen :

Recombinant human Cdc25c.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG1

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

cell division cycle 25 homolog C(S. pombe)

Synonyms :

Protein Cdc25c ; Cdc25c ;

Protein Name :

M-phase inducer phosphatase 3

Molecular Weight :

50896 MW

Protein Function :

CDC25C: Functions as a dosage-dependent inducer in mitoticcontrol. Tyrosine protein phosphatase required for progression ofthe cell cycle. When phosphorylated, highly effective inactivating G2 cells into prophase. Directly dephosphorylates CDK1and activates its kinase activity.

Subcellular Localization :

CDC25C: Nucleus Cdc25c: Nucleus.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot.

Sequence Similarities :

Belongs to the MPI phosphatase family.

Background :

Cell division sycle (CDC25) gene product is a protein-tyrosine phosphatase, activates a partially purified p34 (cdc2)/cyclin B complex. The cdc25 protein also shares homology with a protein phosphatase with activity against both tyrosine and serine (and thus probably threonine) phosphate residues. CDC25C is expressed predominantly in G2 phase in healer cells. The human gene encodes a protein with a predicted molecular mass of 53,000 daltons whose C-terminal domain shares about 37% sequence identity with the fission yeast cdc25 mitotic inducer. CDC25C gene is mapped to 5q31.

Research Category :

Cell Biology, Cell Cycle, Epigenetics and Nuclear Signaling, Kinases/Phosphatases