Anti-Cathepsin D Ctsd Monoclonal Antibody | Boster MA1013 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Cathepsin D Ctsd Monoclonal Antibody

catalog :

MA1013

quantity :

100μg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CTD-19

The same clone is also sold as:

Invitrogen: MA1-26773, MA5-32991
Abnova: MAB1513
Abcam: ab6313
MilliporeSigma: C0715

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

SKU :

MA1013

Product Name :

Anti-Cathepsin D Ctsd Monoclonal Antibody

Size :

100μg/vial

Clonality :

Monoclonal

Clone Number :

CTD-19

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC, WB

Application Details :

Immunohistochemistry (Paraffin-embedded Section), 1-2µg/ml, Human, By Heat. Western blot, 0.5-1µg/ml, Human.

Application Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Cathepsin D Ctsd Monoclonal Antibody catalog # MA1013. Tested in IHC, WB applications. This antibody reacts with Human.

Concentration :

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Gene Name :

CTSD

Uniprot ID :

P24268

Immunogen :

Human liver cathepsin D.

Form :

Lyophilized

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Cross-reactivity :

No cross reactivity with other proteins

Isotype :

Mouse IgG2a

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Gene Full Name :

Cathepsin D

Synonyms :

Cathepsin D; 3.4.23.5; Cathepsin D 12 kDa light chain; Cathepsin D 9 kDa light chain; Cathepsin D 34 kDa heavy chain; Cathepsin D 30 kDa heavy chain; Ctsd;

Protein Name :

Cathepsin D

Molecular Weight :

44681 MW

Protein Function :

Acid protease active in intracellular protein breakdown.

Subcellular Localization :

Lysosome. Melanosome. Secreted, extracellular space.

Tissue Specificity :

CTSD: Expressed in the aorta extrcellular space (atprotein level).

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Sequence Similarities :

Belongs to the peptidase A1 family.

Background :

Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively.

Research Category :

Cancer, Cell Adhesion Proteins, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Membrane Proteins, Neuroscience, Proteolysis / Ubiquitin, Proteolytic Enzymes, Signal Transduction